研究業績

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学会:酵素補充療法

国際学会、シンポジウム等招待講演

2023年度

  • Kuroda M, Aso M, Yamamoto TT, Wada J, Ishikawa K, Maezawa Y, Teramoto N, Kubota Y, Tawada A, Aoyagi Y, Asada S, Kirinashizawa M, Onitake A, Matsuura Y, Yasunaga K, Konno S, Nishino K, Yamamoto M, Miyoshi J, Kobayashi N, Tanio M, Ikeuchi T, Igari H, Mitsukawa N , Hanaoka H, Saito Y, Yokote K : Sustained LCAT replacement in patient with familial LCAT deficiency in clinical trial of ex vivo gene/cell therapy using autologous preadipocytes. (Oral presentation) ESGCT 30TH ANNUAL CONGRESS. 2023.10.24-27. Brussels. Belgium
  • 黒田正幸、石川耕、前澤善朗、和田淳、窪田吉孝、三川信之、太和田彩子、山本徳男、麻生雅是、花岡英紀、齋藤康、横手幸太郎 : 家族性LCAT欠損症を対象としたex vivo脂肪細胞遺伝子治療のfirst in human試験. 第29回日本遺伝子細胞治療学会学術集会プレナリーセッション. 2023. 9. 11-13. 大阪
  • Aso M, Yamamoto TT, Kuroda M, Wada J, Kubota Y, Ishikawa K, Maezawa Y, Teramoto N, Tawada A, Asada S, Aoyagi Y, Kirinashizawa M, Onitake A, Matsuura Y, Yasunaga K, Konno S, Nishino K, Yamamoto M, Miyoshi J, Kobayashi N, Tanio M, Ikeuchi T, Igari H, Mitsukawa N, Hanaoka H, Yokote K, Saito Y : One and Done Gene and Cell Therapy for Familial LCAT Deficiency Using LCAT Gene Transduced Human Adipocytes. The American Society of Gene & Cell Therapy (ASGCT), 26th Annual Meeting. 2023. 5.16-20. Los Angeles, CA.

2019年度

  • Kuroda M, Yamamoto T, Yokote K, Saito Y, Aso M : Gene/Cell Therapy for familial LCAT deficiency by Genetically Modified Adipocytes, GMAC. 3rd Annual cell therapy World ASIA 2019. 2019. 9. 18-19. 東京. 

2018年度

  • Kobayashi N, Kuroda M, Yokote K, Saito Y, Aso M : Genetically Modified Adipocytes, GMAC, for Regenerative Cell Medicine and Gene Therapy. 5th International Symposium for Medicinal Sciences(第5回国際創薬シンポジウム), 3/22/2019 千葉
  • Kuroda M, Ishikawa K, Kubota Y, Mitsukawa N, Tawada A, Aoyagi Y, Asada S, Yamamoto T, Konno S, Tanaka S, Tanio M, Aso M, Saito Y, Wada J. Yokote K : First in human clinical trial of treatment of familial LCAT deficiency syndrome by self-transplantation of therapeutic-enzyme secreting adipocytes. 25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress, 9/4-9/7/2018, 京都
  • Aoyagi Y, Kuroda M, Asada S, Onitake A, Kirinashizawa M, Yamamoto T, Tanaka S, Konno S, Tanio M, Saito Y, Yokote K, Aso M :  A novel technology for lifelong treatment of intractable plasma protein deficiency: Ex vivo-manipulated adipocytes for sustained secretion of therapeutic proteins. 25th TERMIS (Tissue Engineering and Regenerative Medicine International Society) World Congress, 9/4-9/7/2018, 京都

2016年度

  • Kuroda M, Bujo H, Yokote K, Saito Y, Aso M : Ex Vivo Gene-manipulated Mature Adipocytes: Novel Gene Therapy Medicine for Sustained Protein Replacement Therapy of Variety of Intractable Diseases. 3rd International Symposium for Medicinal Sciences(第3回国際創薬シンポジウム), 3/26/2017 仙台

2014年度

  • Aso M, Kuroda M, Asada S, Aoyagi Y, Onitake A, Tanaka S, Konno S, Tanio M, Bujo H, Saito Y, and Yokote K : Novel ex vivo gene manipulation technology of mature adipocytes for sustained protein replacement therapy of variety of intractable diseases. The XXIInd Annual ESCGT Congress in collaboration with the NVGCT. 2014/ 10 ハーグ(オランダ).
  • Kuroda M, Aoyagi Y, Asada S, Aso M, Bujo H, Saito Y, and Yokote K : Development of ex vivo gene therapy for familial LCAT deficiency syndrome by self-transplantation of therapeutic-enzyme secreting adipocytes. The XXIInd Annual ESCGT Congress in collaboration with the NVGCT. 2014/10 ハーグ(オランダ).
  • Aoyagi Y, Kuroda M, Asada S, Aso M, Yokote K, Saito Y, and Bujo H : Treatment of familial LCAT deficiency syndrome by self-transplantation of therapeutic-enzyme secreting adipocytes. The 9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress. 2014/9 京都.
  • Kuroda M, Holleboom AG, Stroes E, Asada S, Aoyagi Y, Kamata K, Yamashita S, Ishibashi S, Saito Y, Bujo H : Lipoprotein subfractions highly associated with renal damage in familial LCAT deficiency. The 9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress. 2014/9 京都.
  • Kuroda M, Yokote K, Bujo H, Asada S, Aoyagi Y, Aso M, and Saito Y : Translational clinical research for treatment of familial LCAT deficient patients through transplantation of ex vivo gene-transduced autologous adipocytes. The 18th International Vascular Biology Meeting. 2014/4 京都.

2011年度

  • Kuroda M, Asada S, Aoyagi Y, Tanaka S, Konno S, Tanio M, Aso M, Saito Y, and Bujo H : Proliferative Adipocytes as Therapeutic Gene Vehicle toward Sustained Protein Replacement Therapy. "The American Society of Gene & Cell Therapy (ASGCT) 14th Annual Meeting", 2011/05/18-21

2010年度

  • Bujo H : Novel gene therapy using the autologous preadipocyte transplantation for the patients with LCAT deficiency. Amsterdam University Academic Medical Center (AMC) Vascular Medicine Symposium. Special lecture.
  • Bujo H : LR11, a novel biomarker for cardiovascular diseases. Amsterdam University Academic Medical Center (AMC) Vascular Medicine Symposium. Special lecture.
  • Bujo H : Dyslipidemia and cardiovascular disease. Vietnam Nutrition Association The 5th National Nutrition Scientific Conference. Invited lecture.
  • Bujo H : Dyslipidemia and cardiovascular disease. Ho Chi Minh City University of Medicine and Pharmacy Topic Course on dyslipidemia and diabetes. Invited lecture.

国内学会、シンポジウム等招待講演

2023年度

2022年度

2020年度

2019年度

2018年度

2017年度

2016年度

2015年度

2014年度

2013年度

2011年度

2010年度

2009年度