Journal
2017 | 2018 | 2019 | 2020 | 2021 | 2022
2017
- Nakajima-Adachi, H., Shibahara, K., Fujimura, Y., Takeyama, J., Hiraide, E., Kikuchi, A., Murakami, H., Hosono, A., Nochi, T., Wakatsuki, Y., Shimojo, N., Kaminogawa, S., Sato, R., Kiyono, H. and Hachimura, S. 2017. Critical role of intestinal interleukin-4 modulating regulatory T Cells for desensitization, tolerance, and inflammation of food allergy. PLoS One. 12: e0172795. (2017)
(Critical role of intestinal interleukin-4 modulating regulatory T cells for desensitization, tolerance, and inflammation of food allergy - PubMed (nih.gov)) - Shimokawa, C., Kanaya, T., Hachisuka, M., Ishiwata, K., Hisaeda, H., Kurashima, Y., Kiyono, H. , Tomohiro, Y., Kaisho, T. and Ohno, H. 2017. Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. Immunity. 46: 863-874. (2017)
(Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections - PubMed (nih.gov)) - Ogawa, T., Kashima, K., Yuki, Y., Mejima, M., Kurokawa, S., Kuroda, M., Okazawa, A., Kiyono, H. and Ohta, D. 2017. Seed metabolome analysis of a transgenic rice line expressing cholera toxin B-subunit. Sci. Rep. 7: 5196. (2017)
(Seed Metabolome Analysis of a Transgenic Rice Line Expressing Cholera Toxin B-subunit - PubMed (nih.gov)) - Kishikawa, S., Sato, S., Kaneto, S., Uchino, S., Kohsaka, S., Nakamura, S. and Kiyono, H. 2017. Allograft inflammatory factor 1 (Aif1) is a regulator of transcytosis in M cells. Nature Commun. 8: 14509. (2017)
(Allograft inflammatory factor 1 is a regulator of transcytosis in M cells - PubMed (nih.gov)) - Toyoshima, S., Wakamatsu, E., Ishida, Y., Obata, Y., Kurashima, Y., Kiyono, H. and Abe, R. 2017. The spleen is the site where mast cells are induced in the development of food allergy. Int. Immunol. 29: 31-45. (2017)
(The spleen is the site where mast cells are induced in the development of food allergy - PubMed (nih.gov)) - Azegami, T., Yuki, Y., Sawada, S., Mejima, M., Ishige, K., Akiyoshi, K., Itoh, H. and Kiyono, H. 2017. Nanogel-based nasal ghrelin vaccine prevents obesity. Mucosal Immunol. 10: 1351-1360. (2017)
(Nanogel-based nasal ghrelin vaccine prevents obesity - PubMed (nih.gov)) - Tada, R., Muto, S., Iwata, T., Hidaka, A., Kiyono, H. , Kunisawa, J. and Aramaki, Y. 2017. Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulation augments antigen-specific immune responses in mice. BMC Biotechnol. 10: 68. (2017)
(Attachment of class B CpG ODN onto DOTAP/DC-chol liposome in nasal vaccine formulations augments antigen-specific immune responses in mice - PubMed (nih.gov)) - Furuta, Y., Tsai, S.H., Kinoshita, M., Fujimoto, K., Okumura, R., Umemoto, E., Kurashima, Y., Kiyono, H. , Kayama, H. and Takeda, K. 2017. E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine. PLoS One. 12: e0172509. (2017)
(E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine - PubMed (nih.gov)) - Jinnohara, T., Kanaya, T., Hase, K., Sakakibara, S., Kato, T., Tachibana, N., Sasaki, T., Hashimoto, Y., Sato, T., Watarai, H., Kunisawa, J., Shibata, N., Williams, I., Kiyono, H. and Ohno, H. 2017. IL-22 BP dictates characteristics of Peyer’s patch follicle-associated epithelium for antigen uptake. J. Exp. Med. 214: 1607-1618. (2017)
(IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake - PubMed (nih.gov)) - Kim, S.H., Cho, B.H., Kiyono, H. and Jang, Y.S. 2017. Microbiota-derived butyrate suppresses group 3 innate lymphoid cells in terminal ileal Peyer’s patches. Sci. Rep. 7: 3980. (2017)
(Microbiota-derived butyrate suppresses group 3 innate lymphoid cells in terminal ileal Peyer's patches - PubMed (nih.gov)) - Takahashi, Y., Sato, S., Kurashima, Y., Lai, C-Y., Otsu, M., Hayashi, M., Yamaguchi, T. and Kiyono, H. 2017. Reciprocal inflammatory signaling between intestinal epithelial cells and adipocytes in the absence of immune cells. EbioMedicine. 23: 34-45. (2017)
(Reciprocal Inflammatory Signaling Between Intestinal Epithelial Cells and Adipocytes in the Absence of Immune Cells - PubMed (nih.gov)) - Koyanagi, N., Imai, T., Shindo, K., Sato, A., Fujii, W., Ichinohe, T., Takemura, N., Kakuta, S., Uematsu, S., Kiyono, H. , Maruzuru, Y., Arii, J., Kato, A. and Kawaguchi, Y. 2017. Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis. J. Clin. Invest. 127: 3784-3795. (2017)
(Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis - PubMed (nih.gov)) - Ito, T., Hirose, K., Saku, A., Kono, K., Takatori, H., Tamachi, T., Goto, Y., Renauld, J.C., Kiyono, H. and Nakajima, H. 2017. IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite-induced asthma models. J. Exp. Med. 214: 3037- 3050. (2017)
(IL-22 induces Reg3γ and inhibits allergic inflammation in house dust mite-induced asthma models - PubMed (nih.gov))
2018
- Takahashi, Y., Sato, S., Kurashima, Y., Yamamoto, T., Kurokawa, S., Yuki, Y., Takemura, N., Uematsu, S., Lai, C.Y., Otsu, M., Matsuno, H., Osawa, H., Mizushima, T., Nishimura, J., Hayashi, M., Yamaguchi, T. and Kiyono, H. 2018. A refined culture system for human induced pluripotent stem cell-derived intestinal epithelial organoids. Stem Cell Reports. 10: 314-328. (2018)
(A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids - PubMed (nih.gov)) - Azegami, T., Yuki, Y., Hayashi, K., Hishikawa, A., Sawada, S.I., Ishige, K., Akiyoshi, K., Kiyono, H. and Itoh, H. 2018. Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents. J. Hypertens. 36: 387-394. (2018)
(Intranasal vaccination against angiotensin II type 1 receptor and pneumococcal surface protein A attenuates hypertension and pneumococcal infection in rodents - PubMed (nih.gov)) - Nagatake, T., Shiogama, Y., Inoue, A., Kikuta, J., Honda, T., Tiwari, P., Kishi, T., Yanagisawa, A., Isobe, Y., Matsumoto, N., Shimojou, M., Morimoto, S., Suzuki, H., Hirata, S.I., Steneberg, P., Edlund, H., Aoki, J., Arita, M., Kiyono, H. , Yasutomi, Y., Ishii, M., Kabashima, K. and Kunisawa, J. 2018. The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques. J. Allergy Clin. Immunol. 142: 470-484.e12. (2018)
(The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques - PubMed (nih.gov)) - Suzuki, H., Nagatake, T., Nasu, A., Lan, H., Ikegami, K., Setou, M., Hamazaki, Y., Kiyono, H. , Yagi, K., Kondoh, M. and Kunisawa, J. 2018. Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice. Sci. Rep. 8: 2904. (2018)
(Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice - PubMed (nih.gov)) - Takemura, N., Kurashima, Y., Mori, Y., Okada, K., Ogino, T., Osawa, H., Matsuno, H., Aayam, L., Kaneto, S., Park, E.J., Sato, S., Matsunaga, K., Tamura, Y., Ouchi, Y., Kumagai, Y., Kobayashi, D., Suzuki, Y., Yoshioka, Y., Nishimura, J., Mori, M., Ishii, K.J., Rothenberg, M.E., Kiyono, H. , Akira, S. and Uematsu, S. 2018. Eosinophil depletion suppresses radiation-induced small intestinal fibrosis. Sci. Transl. Med. 21: 10(429). (2018)
(Eosinophil depletion suppresses radiation-induced small intestinal fibrosis - PubMed (nih.gov)) - Hirukawa, S., Sagara, H., Kaneto, S., Kondo, T., Kiga, K., Sanada, T., Kiyono, H. and Mimuro, H. 2018. Characterization of morphological conversion of Helicobacter pylori under anaerobic conditions. Microbiol. Immunol. 62: 221-228. (2018)
(Characterization of morphological conversion of Helicobacter pylori under anaerobic conditions - PubMed (nih.gov)) - Ouchi, Y., Patil, A., Tamura, Y., Nishimasu, H., Negishi, A., Paul, S.K., Takemura, N., Satoh, T., Kimura, Y., Kurachi, M., Nureki, O., Nakai, K., Kiyono, H. and Uematsu, S. 2018. Generation of tumor antigen-specific murine CD8+ T cells with enhanced anti-tumor activity via highly efficient CRISPR/Cas9 genome editing. Int. Immunol. 30:141-154. (2018)
(Generation of tumor antigen-specific murine CD8+ T cells with enhanced anti-tumor activity via highly efficient CRISPR/Cas9 genome editing - PubMed (nih.gov)) - Niimi, K., Usami, K., Fujita, Y., Abe, M., Furukawa, M., Suyama, Y., Sakai, Y., Kamioka, M., Shibata, N., Park, E.J., Sato, S., Kiyono, H. , Yoneyama, H., Kitazawa, H., Watanabe, K., Nochi, T. and Aso, H. 2018. Development of immune and microbial environments is independently regulated in the mammary gland. Mucosal Immunol. 11: 643-653. (2018)
(Development of immune and microbial environments is independently regulated in the mammary gland - PubMed (nih.gov)) - Shibata, N., Kunisawa, J., Hosomi, K., Fujimoto, Y., Mizote, K., Kitayama, N., Shimoyama, A., Mimuro, H., Sato, S., Kishishita, N., Ishii, K.J., Fukase, K. and Kiyono, H. 2018. Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity. Mucosal Immunol. 11: 693-702. (2018)
(Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity - PubMed (nih.gov)) - Tada, R., Suzuki, H., Takahashi, S., Negishi, Y., Kiyono, H. Kunisawa, Y. and Aramaki, Y. 2018. Nasal vaccination with pneumococcal surface protein A in combination with cationic liposomes consisting of DOTAP and DC-chol confers antigen-mediated protective immunity against Streptococcus pneumoniae infections in mice. Int. Immunopharm. 61: 385–393. (2018)
(Nasal vaccination with pneumococcal surface protein A in combination with cationic liposomes consisting of DOTAP and DC-chol confers antigen-mediated protective immunity against Streptococcus pneumoniae infections in mice - PubMed (nih.gov)) - Tada, R., Hidaka, A., Kiyono, H. , Kunisawa, J. and Aramaki, Y. 2018. Intranasal administration of cationic liposomes enhanced granulocyte-macrophage colony-stimulating factor expression and this expression is dispensable for mucosal adjuvant activity. BMC Research Notes. 11:472. (2018)
(Intranasal administration of cationic liposomes enhanced granulocyte-macrophage colony-stimulating factor expression and this expression is dispensable for mucosal adjuvant activity - PubMed (nih.gov)) - Tada, R., Yamanaka, D., Ogasawara, M., Saito, M., Ohno, N., Kiyono, H. , Kunisawa, J. and Aramaki, Y. 2018. Polymeric caffeic acid is a safer mucosal adjuvant that augments antigen-specific mucosal and systemic immune responses in mice. Mol. Pharm. 15: 4226-4234. (2018)
(Polymeric Caffeic Acid Is a Safer Mucosal Adjuvant That Augments Antigen-Specific Mucosal and Systemic Immune Responses in Mice - PubMed (nih.gov)) - Sato, S., Hisaie, K., Kurokawa, S., Suzki, A., Sakon, N., Uchida, Y., Yuki, Y. and Kiyono, H. 2018. Human Norovirus Propagation in Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells. Cell. Mol. Gastro. Hepatol. 7: 686-688.e5. (2018)
(Human Norovirus Propagation in Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells - PubMed (nih.gov))
2019
- Tiwari, P., Nagatake, T., Hirata, S.I., Sawane, K., Saika, A., Shibata, Y., Morimoto, S., Honda, T., Adachi, J., Abe, Y., Isoyama, J., Tomonaga, T., Kiyono, H. , Kabashima, K. and Kunisawa, J. 2019. Dietary coconut oil ameliorates skin contact hypersensitivity through mead acid production in mice. Allergy. 74: 1522-1532. (2019)
(Dietary coconut oil ameliorates skin contact hypersensitivity through mead acid production in mice - PubMed (nih.gov)) - Hashizume-Takizawa, T., Shibata, N., Kurashima, Y., Kiyono, H. , Kurita-Ochiai, T. and Fujihashi, K. 2019. Distinct roles for Peyer's patch B cells for induction of antigen-specific IgA antibody responses in mice administered oral recombinant Salmonella. Int. Immunol. 31: 531-541. (2019)
(Distinct roles for Peyer's patch B cells for induction of antigen-specific IgA antibody responses in mice administered oral recombinant Salmonella - PubMed (nih.gov)) - Saku, A., Hirose, K., Ito, T., Iwata, A., Sato, T., Kaji, H., Tamachi, T., Suto, A., Goto, Y., Domino, S.E., Narimatsu, H., Kiyono, H. and Nakajima, H. 2019. Fructosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite-induced airway inflammation. J. Allergy Clin. Immunol. 144: 698-709.e9. (2019)
(Fucosyltransferase 2 induces lung epithelial fucosylation and exacerbates house dust mite-induced airway inflammation - PubMed (nih.gov)) - Nishida, K., Hasegawa, A., Yamasaki, S., Uchida, R., Ohashi, W., Kurashima, Y., Kunisawa, J., Kimura, S., Iwanaga, T., Watarai, H., Hase, K., Ogura, H., Nakayama, M., Kashiwakura, J., Okayama, Y., Kubo, M., Ohara, O., Kiyono, H. , Koseki, H., Murakami, M. and Hirano, T. 2019. Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis. Sci. Rep. 9: 10842. (2019)
(Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis - PubMed (nih.gov)) - Noval, R.M., Wakita, D., Franklin, M.K., Carvalho, T.T., Abolhesn, A., Gomez, A.C., Fishbein, M.C., Chen, S., Lehman, T.J., Sato, K., Shibuya, A., Fasano, A., Kiyono, H. , Abe, M., Tatsumoto, N., Yamashita, M., Crother, T.R., Shimada, K. and Arditi, M. 2019. Intestinal permeability and IgA provoke immune vasculitis linked to cardiovascular inflammation. Immunity. 51: 508-521.e6. (2019)
(Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation - PubMed (nih.gov)) - Fujimoto, K., Kawaguchi, Y., Shimohigoshi, M., Gotoh, Y., Nakano, Y., Usui, Y., Hayashi, T., Kimura, Y., Uematsu, M., Yamamoto, T., Akeda, Y., Rhee, J.H., Yuki, Y., Ishii, K.J., Crowe, S.E., Ernst, P.B., Kiyono, H. and Uematsu, S. 2019. Antigen-specific mucosal immunity regulates development of intestinal bacteria- mediated diseases. Gastroenterology. 157: 1530-1543.e4. (2019)
(Antigen-Specific Mucosal Immunity Regulates Development of Intestinal Bacteria-Mediated Diseases - PubMed (nih.gov)) - Joo, S., Suwanto, A., Sato, A., Nakahashi-Ouchida, R., Mori, H., Uchida, Y., Sato, S., Kurashima, Y., Yuki, Y., Fujihashi, K., Kawaguchi, Y. and Kiyono, H. 2019. A role for the CCR5-CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization. Mucosal Immunol. 12: 1391-1403. (2019)
(A role for the CCR5-CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization - PubMed (nih.gov)) - Tada, R., Ohshima, A., Tanazawa, Y., Ohmi, A., Takahashi, S., Kiyono, H. , Kunisawa, J., Aramaki, Y. and Negishi, Y. 2019. Essential role of host double-stranded DNA released from dying cells by cationic liposomes for mucosal adjuvanticity. Vaccines (Basel). 8: 8. (2019)
(Essential Role of Host Double-Stranded DNA Released from Dying Cells by Cationic Liposomes for Mucosal Adjuvanticity - PubMed (nih.gov))
2020
- Takahashi, I., Hosomi, K., Nagatake, T., Tobou, H., Yamamoto, D., Hayashi, I., Kurashima, Y., Sato, S., Shibata, N., Goto, Y., Maruyama, F., Nakagawa, I., Kuwae, A., Abe, A., Kunisawa, J. and Kiyono, H. 2020. Persistent colonization of non-lymphoid tissue-resident macrophages by Stenotrophomonas maltophilia. Int. Immunol. 32: 133-141. (2020)
(Persistent colonization of non-lymphoid tissue-resident macrophages by Stenotrophomonas maltophilia - PubMed (nih.gov)) - Isobe, J., Maeda, S., Obata, Y., Iizuka, K., Nakamura, Y., Fujimura, Y., Kimizuka, T., Hattori, K., Kim, Y-G., Morita, T., Kimura, I., Offermanns, S., Adachi, T., Nakao, A., Kiyono, H. , Takahashi, D. and Hase, K. 2020. Commensal-bacteria-derived butyrate promotes the t-cell-independent IgA response in the colon. Int. Immunol. 32: 243-258. (2020)
(Commensal-bacteria-derived butyrate promotes the T-cell-independent IgA response in the colon - PubMed (nih.gov)) - Yuki, Y., Kurokawa, S., Sato, S., Sasou, A., Matsumoto, N., Suzuki, A., Sakon, N., Goda, Y., Takeyama, N., Miyoshi, T., Marcotte, H., Tanaka, T., Hammarstrom, L. and Kiyono, H. 2020. A heterodimeric antibody fragment for passive immunotherapy against norovirus infection. J. Infect. Dis. 222: 470-478. (2020)
(A Heterodimeric Antibody Fragment for Passive Immunotherapy Against Norovirus Infection - PubMed (nih.gov)) - Nakamura, Y., Mimuro, H., Kunisawa, J., Furusawa, Y., Takahashi, D., Fujimura,Y., Kaisho, T., Kiyono, H. and Hase, K. 2020. Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity. Mucosal Immunol. 13: 679-690. (2020)
(Microfold cell-dependent antigen transport alleviates infectious colitis by inducing antigen-specific cellular immunity - PubMed (nih.gov)) - Wang, Y., Hosomi, K., Shimoyama, A., Yoshii, K., Yamaura, H., Nagatake, T., Nishino, T., Kiyono, H. , Fukase, K. and Kunisawa, J. 2020. Adjuvant activity of synthetic lipid A of alcaligenes, a gut-associated lymphoid tissue-resident commensal bacterium, to augment antigen-specific IgG and Th17 responses in systemic vaccine. Vaccines (Basel). 8: 395. (2020)
(Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine - PubMed (nih.gov)) - Yoshii, K., Hosomi, K., Shimoyama, A., Wang, Y., Yamaura, H., Nagatake, T., Suzuki, H., Lan, H., Kiyono, H. , Fukase, K. and Kunisawa, J. 2020. Chemically synthesized alcaligenes lipid A shows a potent and safe nasal vaccine adjuvant activity for the induction of Streptococcus pneumoniae-specific IgA and Th17 mediated protective Immunity. Microorganisms. 8: 1102. (2020)
(Chemically Synthesized Alcaligenes Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of Streptococcus pneumoniae-Specific IgA and Th17 Mediated Protective Immunity - PubMed (nih.gov)) - Hirata, S., Nagatake, T., Sawane, K., Hosomi, K., Honda, T., Ono, S., Shibuya, N., Saito, E., Adachi, J., Abe, Y., Isoyama, J., Suzuki, H., Matsunaga, A., Tomonaga, T., Kiyono, H. , Kabashima, K., Arita, M. and Kunisawa, J. 2020. Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice. Allergy. 75: 1939-1955. (2020)
(Maternal ω3 docosapentaenoic acid inhibits infant allergic dermatitis through TRAIL-expressing plasmacytoid dendritic cells in mice - PubMed (nih.gov)) - Fujimoto, K., Kimura, Y., Shimohigoshi, M., Satoh, T., Sato, S., Tremmel, G., Uematsu, M., Kawaguchi, Y., Usui, Y., Nakano, Y., Hayashi, T., Kashima, K., Yuki, Y., Yamaguchi, K., Furukawa, Y., Kakuta, M., Akiyama, Y., Yamaguchi, R., Crowe, S.E., Ernst, P.B., Miyano, S., Kiyono, H. , Imoto, S. and Uematsu, S. 2020. Metagenome data on intestinal phage-bacteria associations aids the development of phage therapy against pathobionts. Cell. Host Microbe. 28: 380-389.e9. (2020)
(Metagenome Data on Intestinal Phage-Bacteria Associations Aids the Development of Phage Therapy against Pathobionts - PubMed (nih.gov)) - Hosomi, K., Shibata, N., Shimoyama, A., Uto, T., Nagatake, T., Tojima, Y., Nishino, T., Takeyama, H., Fukase, K., Kiyono, H. and Kunisawa, J. 2020. Lymphoid tissue- resident Alcaligenes establish an intracellular symbiotic environment by creating a unique energy shift in dendritic cells. Front. Microbiol. 11: 561005. (2020)
(Lymphoid Tissue-Resident Alcaligenes Establish an Intracellular Symbiotic Environment by Creating a Unique Energy Shift in Dendritic Cells - PubMed (nih.gov)) - Matsumura, S., Kurashima, Y., Murasaki, S., Morimoto, M., Arai, F., Saito, Y., Katayama, N., Kim, D., Inagaki, Y., Kudo, T., Ernst, P.B., Shimizu, T. and Kiyono, H. 2020. Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation. Sci. Rep. 10: 18351. (2020)
(Stratified layer analysis reveals intrinsic leptin stimulates cryptal mesenchymal cells for controlling mucosal inflammation - PubMed (nih.gov)) - Takasato, Y., Kurashima, Y., Kiuchi, M., Hirahara, K., Murasaki, S., Arai, F., Izawa, K., Kaitani, A., Shimada, K., Saito, Y., Toyoshima, S., Nakamura, M., Fujisawa, K., Okayama, Y., Kunisawa, J., Kubo, M., Takemura, N., Uematsu, S., Akira, S., Kitaura, J., Takahashi, T., Nakayama, T. and Kiyono, H. 2020. Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy. Mucosal Immunol. 14: 640-651. (2020)
(Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy - PubMed (nih.gov))
2021
- Sasou, A., Yuki, Y., Honma, A., Sugiura, K., Kashima, K., Kozuka-Hata, K., Nojima, M., Oyama, M., Kurokawa, S., Maruyama, S., Kuroda, M., Tanoue, S., Takamatsu, N., Fujihashi, K., Goto, E. and Kiyono, H. 2021. Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine. BMC Genomics. 22: 59. (2021)
(Comparative whole-genome and proteomics analyses of the next seed bank and the original master seed bank of MucoRice-CTB 51A line, a rice-based oral cholera vaccine - PubMed (nih.gov)) - Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura,Y., Kiyono, H. , Ishikawa, K., Ampofo, W.K. and Matano, T. 2020. Fecal microbiome composition in healthy adults in Ghana. Jpn. J. Infect. Dis. 74: 42-47. (2020)
(Fecal Microbiome Composition in Healthy Adults in Ghana - PubMed (nih.gov)) - Shimoyama, A., Flaviana, D.L., Yamaura, H., Mizote, K., Palmigiano, A., Pither, M.D., Speciale, I., Uto, T., Masui, S., Sturiale, L., Garozzo, D., Hosomi, K., Shibata, N., Kabayama, K., Fujimoto, Y., Silipo, A., Kunisawa, J., Kiyono, H. , Molinaro, A. and Fukase, K. 2021. Lipopolysaccharide from gut-associated lymphoid tissue-resident alcaligenes faecalis: Complete structure determination and chemical synthesis of its lipid A. Angew. Chem. Int. Ed. Engl. 60: 10023-10031. doi: 10.1002/anie.202012374. Epub 2021 Mar 22. (2021)
(Lipopolysaccharide from Gut-Associated Lymphoid-Tissue-Resident Alcaligenes faecalis: Complete Structure Determination and Chemical Synthesis of Its Lipid A - PubMed (nih.gov)) - Tada, R., Ogasawara, M., Yamanaka, D., Sakurai, Y., Negishi, Y., Kiyono, H. , Ohno, N., Kunisawa, J. and Aramaki, Y. 2021. Enzymatically polymerised polyphenols prepared from various precursors potentiate antigen-specific immune responses in both mucosal and systemic compartments in mice. PLoS One. 16: e0246422. (2021)
(Enzymatically polymerised polyphenols prepared from various precursors potentiate antigen-specific immune responses in both mucosal and systemic compartments in mice - PubMed (nih.gov)) - Fujimoto, K., Kimura, Y., Allegretti, J.R., Yamamoto, M., Zhang, Y.Z., Katayama, K., Tremmel, G., Kawaguchi, Y., Shimohigoshi, M., Hayashi, T., Uematsu, M., Yamaguchi, K., Furukawa, Y., Akiyama, Y., Yamaguchi, R., Crowe, S.E., Ernst, P.B., Miyano, S., Kiyono, H. , Imoto, S. and Uematsu, S. 2021. Functional restoration of bacteriomes and viromes by fecal microbiota transplantation. Gastroenterology. 160: 2089-2102.e12. doi: 10.1053/j.gastro.2021.02.013. Epub 2021 Feb 9. (2021)
(Functional Restoration of Bacteriomes and Viromes by Fecal Microbiota Transplantation - PubMed (nih.gov)) - Lee, J., Mohsen, A., Banerjee, A., McCullough, L.D., Mizuguchi, K., Shimaoka, M., Kiyono, H. and Park, E.J. 2021. Distinct age-specific miregulome profiling of isolated small and large intestinal epithelial cells in mice. Int. J. Mol. Sci. 22: 3544. (2021)
(Distinct Age-Specific miRegulome Profiling of Isolated Small and Large Intestinal Epithelial Cells in Mice - PubMed (nih.gov)) - Yuki, Y., Uchida, Y., Sawada, S., Nakahashi-Ouchida, R., Sugiura, K., Mori, H., Yamanoue, T., Machita, T., Honma, A., Kurokawa, S., Mukerji, R., Briles, D.E., Akiyoshi, K. and Kiyono, H. 2021. Characterization and specification of a trivalent protein-based Pneumococcal vaccine formulation using an adjuvant-free nanogel nasal delivery system. Mol. Pharm. 18: 1582-1592. doi: 10.1021/acs.molpharmaceut.0c01003. Epub 2021 Feb 23. (2021)
(Characterization and Specification of a Trivalent Protein-Based Pneumococcal Vaccine Formulation Using an Adjuvant-Free Nanogel Nasal Delivery System - PubMed (nih.gov)) - Mizutani, T., Aboagye, S.Y., Ishizaka, A., Afum, T., Mensah, G.I., Asante-Poku, A., Asandem, D.A., Parbie, P.K., Abana, C.Z., Kushitor, D., Bonney, E.Y., Adachi, M., Hori, H., Ishikawa, K., Matano, T., Taniguchi, K., Opare, D., Arhin, D., Asiedu-Bekoe, F., Ampofo, W.K., Yeboah-Manu, D., Koram, K.A., Anang, A.K. and Kiyono, H. 2021. Gut microbiota signature of pathogen-dependent dysbiosis in viral gastroenteritis. Sci. Rep. 11: 13945. doi: 10.1038/s41598-021-93345-y. (2021)
(Gut microbiota signature of pathogen-dependent dysbiosis in viral gastroenteritis - PubMed (nih.gov)) - Wang, Y., Hosomi, K., Shimoyama, A., Yoshii, K., Nagatake, T., Fujimoto, Y., Kiyono, H. , Fukase, K. and Kunisawa, J. 2021. Lipopolysaccharide derived from the lymphoid-resident commensal bacteria Alcaligenes faecalis functions as an effective nasal adjuvant to augment IgA antibody and Th17 cell responses. Front. Immunol. 12: 699349. doi: 10.3389/fimmu.2021.699349. eCollection 2021. (2021)
(Lipopolysaccharide Derived From the Lymphoid-Resident Commensal Bacteria Alcaligenes faecalis Functions as an Effective Nasal Adjuvant to Augment IgA Antibody and Th17 Cell Responses - PubMed (nih.gov)) - Parbie, P.K., Mizutani, T., Ishizaka, A., Kawana-Tachikawa, A., Runtuwene, L.R., Seki, S., Abana, C.Z., Kushitor, D., Bonney, E.Y., Ofori, S.B., Uematsu, S., Imoto, S., Kimura, Y., Kiyono, H. , Ishikawa, K., Ampofo, W.K. and Matano, T. 2021. Dysbiotic fecal microbiome in HIV-1 infected individuals in Ghana. Front. Cell Infect. Microbiol. 11: 646467. doi: 10.3389/fcimb.2021.646467. eCollection 2021. (2021)
(Dysbiotic Fecal Microbiome in HIV-1 Infected Individuals in Ghana - PubMed (nih.gov)) - Nakahashi-Ouchida, R., Uchida, Y., Yuki, Y., Katakai, Y., Yamanoue, T., Ogawa, H., Munesue, Y., Nakano, N., Hanari, K., Miyazaki, T., Saito, Y., Umemoto, S., Sawada, S.I., Mukerji, R., Briles, D.E., Yasutomi, Y., Akiyoshi, K. and Kiyono, H. 2021. A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci. Vaccine. 39: 3353-3364. doi: 10.1016/j.vaccine.2021.04.069. Epub 2021 May 17. (2021)
(A nanogel-based trivalent PspA nasal vaccine protects macaques from intratracheal challenge with pneumococci - PubMed (nih.gov)) - Takasato, Y., Kurashima, Y., Kiuchi, M., Hirahara, K., Murasaki, S., Arai, F., Izawa, K., Kaitani, A., Shimada, K., Saito, Y., Toyoshima, S., Nakamura, M., Fujisawa, K., Okayama, Y., Kunisawa, J., Kubo, M., Takemura, N., Uematsu, S., Akira, S., Kitaura, J., Takahashi, T., Nakayama, T. and Kiyono, H. 2021. Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy. Mucosal Immunol. 14: 640-651. doi: 10.1038/s41385-020-00358-3. Epub 2020 Dec 10. (2021)
(Orally desensitized mast cells form a regulatory network with Treg cells for the control of food allergy - PubMed (nih.gov)) - Liu, Z., Hosomi, K., Shimoyama, A., Yoshii, K., Sun, X., Lan, H., Wang, Y., Yamaura, H., Kenneth, D., Saika, A., Nagatake, T., iyono, H. , Fukase, K. and Kunisawa, J. 2021. Chemically synthesized alcaligenes lipid A as an adjuvant to augment immune responses to haemophilus influenzae type B conjugate vaccine. Front. Pharmacol. 12: 763657. doi: 10.3389/fphar.2021.763657. eCollection 2021. (2021)
(Chemically Synthesized Alcaligenes Lipid A as an Adjuvant to Augment Immune Responses to Haemophilus Influenzae Type B Conjugate Vaccine - PubMed (nih.gov)) - Tada, R., Hidaka, A., Tanazawa, Y., Ohmi, A., Muto, S., Ogasawara, M., Saito, M., Ohshima, A., Iwase, N., Honjo, E., Kiyono, H. , Kunisawa, J. and Negishi, Y. 2021. Role of interleukin-6 in antigen-specific mucosal immunoglobulin A induction by cationic liposomes. Int. Immunopharmacol. 101 (Pt A): 108280. doi: 10.1016/j.intimp.2021.108280. Epub 2021 Oct 29. (2021)
(Role of interleukin-6 in antigen-specific mucosal immunoglobulin A induction by cationic liposomes - PubMed (nih.gov)) - Ishizaka, A., Koga, M., Mizutani, T., Lim, L.A., Adachi, E., Ikeuchi, K., Ueda, R., Aoyagi, H., Tanaka, S., Kiyono, H. , Matano, T., Aizaki, H., Yoshio, S., Mita, E., Muramatsu, M., Kanto, T., Tsutsumi, T. and Yotsuyanagi, H. 2021. Prolonged gut dysbiosis and fecal excretion of hepatitis A virus in patients infected with human immunodeficiency virus. Viruses. 13: 2101. doi: 10.3390/v13102101. (2021)
(Prolonged Gut Dysbiosis and Fecal Excretion of Hepatitis A Virus in Patients Infected with Human Immunodeficiency Virus - PubMed (nih.gov)) - Usami, K., Niimi, K., Matsuo, A., Suyama, Y., Sakai, Y., Sato, S., Fujihashi, K., Kiyono, H. , Uchino, S., Furukawa, M., Islam, J., Ito, K., Moriya, T., Kusumoto, Y., Tomura, M., Hovey, R.C., Sugawara, J., Yoneyama, H., Kitazawa, H., Watanabe, K., Aso, H. and Nochi, T. 2021. The gut microbiota induces Peyer's-patch-dependent secretion of maternal IgA into milk. Cell Rep. 36: 109655. doi: 10.1016/j.celrep.2021.109655. (2021)
(The gut microbiota induces Peyer's-patch-dependent secretion of maternal IgA into milk - PubMed (nih.gov)) - Ishizaka, A., Koga, M., Mizutani, T., Parbie, P.K., Prawisuda, D., Yusa, N., Sedohara, A., Kikuchi, T., Ikeuchi, K., Adachi, E., Koibuchi, T., Furukawa, Y., Tojo, A., Imoto, S., Suzuki, Y., Tsutsumi, T., Kiyono, H. , Matano, T. and Yotsuyanagi, H. 2021. Unique gut microbiome in HIV patients on antiretroviral therapy (ART) suggests association with chronic inflammation. Microbiol. Spectrum. 9: e0070821. doi: 10.1128/Spectrum.00708-21. Epub 2021 Aug 11. (2021)
(Unique Gut Microbiome in HIV Patients on Antiretroviral Therapy (ART) Suggests Association with Chronic Inflammation - PubMed (nih.gov)) - Ono-Ohmachi, A., Yamada, S., Uno, S., Tamai, M., Soga, K., Nakamura, S., Udagawa, N., Nakamichi, Y., Koide, M., Morita, Y., Takano, T., Itoh, T., Kakuta, S., Morimoto, C., Matsuoka, S., Iwakura, Y., Tomura, M., Kiyono, H. , Hachimura, S. and Nakajima-Adachi, H. 2021. Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance. Mucosal Immunol. 14: 1335-1346. doi: 10.1038/s41385-021-00434-2. Epub 2021 Jul 29. (2021)
(Effector memory CD4 + T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance - PubMed (nih.gov)) - Takahashi, Y., Inoue, Y., Kuze, K., Sato, S., Shimizu, M., Kiyono, H. , Yamauchi, Y. and Sato, R. 2021. Comparison of gene expression and activation of transcription factors in organoid-derived monolayer intestinal epithelial cells and organoids. Biosci. Biotechnol. Biochem. 85: 2137-2144. doi: 10.1093/bbb/zbab136. (2021)
(Comparison of gene expression and activation of transcription factors in organoid-derived monolayer intestinal epithelial cells and organoids - PubMed (nih.gov)) - Sasou, A., Yuki, Y., Kurokawa, S., Sato, S., Goda, Y., Uchida, M., Matsumoto, N., Sagara, H., Watanabe, Y., Kuroda, M., Sakon, N., Sugiura, K., Nakahashi-Ouchida, R., Ushijima, H., Fujihashi, K. and Kiyono, H. 2021. Development of antibody-fragment-producing rice for neutralization of human norovirus. Front. Plant Sci. 12: 639953. (2021)
(Development of Antibody-Fragment-Producing Rice for Neutralization of Human Norovirus - PubMed (nih.gov)) - Kurashima, Y., Kigoshi, T., Murasaki, S., Arai, F., Shimada, K., Seki, N., Kim, Y.G., Hase, K., Ohno, H., Kawano, K., Ashida, H., Suzuki, T., Morimoto, M., Saito, Y., Sasou, A., Goda, Y., Yuki, Y., Inagaki, Y., Iijima, H., Suda, W., Hattori, M. and Kiyono, H. 2021. Pancreatic Glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation. Nature Commun. 12: 1067. (2021)
(Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation - PubMed (nih.gov)) - Yuki, Y., Nojima, M., Hosono, O., Tanaka, H., Kimura, Y., Satoh, T., Imoto, S., Uematsu, S., Kurokawa, S., Kashima, K., Mejima, M., Nakahashi-Ouchida, R., Uchida, Y., Marui, T., Yoshikawa, N., Nagamura, F., Fujihashi, K. and Kiyono, H. 2021. Oral MucoRice-CTB vaccine for safety and microbiota-dependent immunogenicity in humans: a phase 1 randomized trial. Lancet Microbe. Sep;2(9):e429-e440. doi: 10.1016/S2666-5247(20)30196-8. Epub 2021 Jun 25. (2021)
(Oral MucoRice-CTB vaccine for safety and microbiota-dependent immunogenicity in humans: a phase 1 randomised trial - PubMed (nih.gov))
2022
- Kamioka, M., Goto, Y., Nakamura, K., Yokoi, Y., Sugimoto, R., Ohira, S., Kurashima, Y., Umemoto, S., Sato, S., Kunisawa, J., Takahashi, Y., Domino, S.E., Renauld, J-C., Nakae, S., Iwakura, Y., Peter B.E., Ayabe, T. and Kiyono, H. 2022. Intestinal commensal microbiota and cytokines regulate Fut2+ Paneth cells for gut defense. Proc. Natl. Acad. Sci. USA. 119: e2115230119. doi: 10.1073/pnas.2115230119. (2022)
(Intestinal commensal microbiota and cytokines regulate Fut2 + Paneth cells for gut defense - PubMed (nih.gov)) - Yuki, Y., Nojima, Kashima, K., Sugiura, K., Maruyama, S., Kurokawa, S., Yamanoue, T., Nakahashi-Ouchida, R., Nakajima, H., Hiraizumi, T., Kohno, H., Goto, E., Fujihashi, K. and Kiyono, H. 2022. Oral MucoRice-CTB vaccine is safe and immunogenic in healthy US adults. Vaccine. 40:3372-3379. doi: 10.1016/j.vaccine.2022.04.051. Epub 2022 Apr 26. (2022)
(Oral MucoRice-CTB vaccine is safe and immunogenic in healthy US adults - PubMed (nih.gov)) - Mizutani, T., Ishizaka, A., Koga, M., Ikeuchi, K., Saito, M., Adachi, E., Yamayoshi, S., Iwatsuki-Horimoto, K., Yasuhara, A., Kiyono, H., Matano, T., Suzuki, Y., Tsutsumi, T., Kawaoka, Y. and Yotsuyanagi, H. 2022. Correlation Analysis between Gut Microbiota Alterations and the Cytokine Response in Patients with Coronavirus Disease during Hospitalization. Microbiol. Spectr. 10:e0168921. doi: 10.1128/spectrum.01689-21. Epub 2022 Mar 7. (2022)
(Correlation Analysis between Gut Microbiota Alterations and the Cytokine Response in Patients with Coronavirus Disease during Hospitalization - PubMed (nih.gov))
Reviews (Refereed)
2017
- Nelson, S., Kiyono, H. and Kurashima, Y. 2017. Epithelial extracellular ATP: an initiator of immunity to parasitic infections. Immunol. Cell Biol. 95:117-118. (2017)
(Epithelial extracellular ATP: an initiator of immunity to parasitic infections - PubMed (nih.gov)) - Azegami, T., Yuki, Y., Hayashi, K., Nakamura, M., Hishikawa, A., Kiyono, H. and Itoh, H. 2016. ISH NIA OS-02 attenuation of hypertension by less-invasive intranasal vaccination against angiotensin II type 1 receptor in spontaneously hypertensive rats. J. Hypertens. 34 Suppl 1: e42. (2016)
(Journal of Hypertension 掲載 リンク貼れませんでした)
2017
- Park, E.J., Shimaoka, M. and Kiyono, H. 2017. MicroRNA-mediated dynamic control of mucosal immunity. Int. Immunol. 29: 157-163. (2017)
(MicroRNA-mediated dynamic control of mucosal immunity - PubMed (nih.gov)) - Kurashima, Y. and Kiyono, H. 2017. Mucosal ecological network of epithelium and immune cells for gut homeostasis and tissue healing. Annu. Rev. Immunol. 35: 119-147. (2017)
(Mucosal Ecological Network of Epithelium and Immune Cells for Gut Homeostasis and Tissue Healing - PubMed (nih.gov)) - Nakahashi-Ouchida, R., Yuki, Y. and Kiyono, H. 2017. Development of a nanogel-based nasal vaccine as a novel antigen delivery system. Expert Rev. Vaccines. 16: 1231-1240. (2017)
(Development of a nanogel-based nasal vaccine as a novel antigen delivery system - PubMed (nih.gov)) - Shibata, N., Kunisawa, J. and Kiyono, H. 2017. Dietary and microbial metabolites in the regulation of host immunity. Front. Microbiol. 8: 2171. (2017)
(Dietary and Microbial Metabolites in the Regulation of Host Immunity - PubMed (nih.gov)) - Kurashima, Y., Yamamoto, D., Nelson, S., Uematsu, S., Ernst, P.B., Nakayama, T. and Kiyono, H. 2017. Mucosal mesenchymal cells: secondary barrier and peripheral educator for the gut immune system. Front. Immunol. 8: 1787. (2017)
(Mucosal Mesenchymal Cells: Secondary Barrier and Peripheral Educator for the Gut Immune System - PubMed (nih.gov))
2018
- Azegami, T., Yuki, Y., Nakahashi-Ouchida, R., Itoh, H. and Kiyono, H. 2018. Nanogel-based nasal vaccines for infectious and lifestyle-related diseases. Mol. Immunol. 98: 19-24. (2018)
(Nanogel-based nasal vaccines for infectious and lifestyle-related diseases - PubMed (nih.gov)) - Nakahashi-Ouchida, R., Yuki, Y. and Kiyono, H. 2018. Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases. Hum. Vaccine Immunother. 14: 2189-2193. (2018)
(Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases - PubMed (nih.gov)) - Inami, A., Kiyono, H. and Kurashima, Y. 2018. ATP as a pathophysiologic mediator of bacteria-host crosstalk in the gastrointestinal tract. Int. J. Mol. Sci. 2018. 19: 2371. (2018)
(ATP as a Pathophysiologic Mediator of Bacteria-Host Crosstalk in the Gastrointestinal Tract - PubMed (nih.gov))
2019
- Tokuhara, D., Kurashima, Y., Kamioka, M., Nakayama, T., Ernst, P.B. and Kiyono, H. 2019. A comprehensive understanding of the gut mucosal immune system in allergic inflammation. Allergol. Int. 68: 17-25. (2019)
(A comprehensive understanding of the gut mucosal immune system in allergic inflammation - PubMed (nih.gov)) - Kiyono, H. and Izuhara, K. 2019. New trends in mucosal immunology and allergy. Allergol. Int. 68: 1-3. (2019)
(New trends in mucosal immunology and allergy - PubMed (nih.gov)) - Kurashima, Y., Tokuhara, D., Kamioka, M., Inagaki, Y. and Kiyono, H. 2019. Intrinsic control of surface immune and epithelial homeostasis by tissue-resident gut stromal cells. Front. Immunol. 19: 1281. (2019)
(Intrinsic Control of Surface Immune and Epithelial Homeostasis by Tissue-Resident Gut Stromal Cells - PubMed (nih.gov)) - Hosomi, K., Kiyono, H. and Kunisawa, J. 2019. Fatty acid metabolism in the host and commensal bacteria for the control of intestinal immune responses and diseases. Gut Microbes. 23:1-9. (2019)
(Fatty acid metabolism in the host and commensal bacteria for the control of intestinal immune responses and diseases - PubMed (nih.gov))
2020
- Osier, F., Ting, J.P.Y., Fraser, J., Lambrecht, B.N., Romano, M., Gazzinelli, R.T., Bortoluci, K.R., Zamboni, D.S., Akbar, A.N., Evans, J., Brown, D.E., Patel, K.D., Wu, Y., Perez, A.B., Pérez, O., Kamradt, T., Falk, C., Barda-Saad, M., Ariel, A., Santoni, A., Annunziato, F., Cassatella, M.A., Kiyono, H. , Chereshnev, V., Dieye, A., Mbow, M., Mbengue, B., Niang, M.D.S. and Suchard, M. 2020. The global response to the COVID-19 pandemic: how have immunology societies contributed? Nat. Rev. Immunol. 10: 594-602. (2020)
(The global response to the COVID-19 pandemic: how have immunology societies contributed? - PubMed (nih.gov))
2021
- Campillo-Gimenez, L., Rios-Covian, D., Rivera-Nieves, J., Kiyono, H. , Chu, H. and Ernst, P.B. 2021. Microbial-driven immunological memory and its potential role in microbiome editing for the prevention of colorectal cancer. Front. Cell. Infect. Microbiol. 11: 752304. doi: 10.3389/fcimb.2021.752304. eCollection 2021. (2021)
(Microbial-Driven Immunological Memory and Its Potential Role in Microbiome Editing for the Prevention of Colorectal Cancer - PubMed (nih.gov)) - Kiyono, H. , Yuki, Y., Nakahashi-Ouchida, R. and Fujihashi, K. 2021. Mucosal vaccines: wisdom from now and then. Int. Immunol. 33: 767-774. doi: 10.1093/intimm/dxab056. (2021)
(Mucosal vaccines: wisdom from now and then - PubMed (nih.gov))
2022
- Zhang, Z., Tanaka, I., Pan, Z., Ernst, P.B., Kiyono, H. , Kurashima, Y. 2022. Intestinal homeostasis and inflammation: gut microbiota at the crossroads of pancreas-intestinal barrier axis. Eur. J. Immunol. Online ahead of print.PMID: 35476255 doi: 10.1002/eji.202149532. (2022)
(Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas-intestinal barrier axis - PubMed (nih.gov))
BOOKS
- Kiyono, H. and Uematsu, S. 2017. Experimental Medicine, Biological Barrier Research Up-to-Date Special Edition. Experimental Medicine, Yodosha, Japan, pp. 1-222. (Japanese) (2017)
(実験医学増刊 Vol.35 No.7 生態バリア 羊土社) - Kiyono, H. and Pascual, D.W. 2020. Mucosal Vaccines, Innovation for Preventing Infectious Diseases, Second Edition. Elsevier. ISBN: 978-0-12-811924-2, pp. 1-915 (2020)
(Mucosal Vaccines : Innovation for Preventing Infectious Diseases 第二版 ACADEMIC PRESS, INC. 洋書)