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Allergy and Clinical Immunology |
Optimization of Infliximab Withdrawal Strategy for Rheumatoid Arthritis (OPTIWIT) |
Link |
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Ophthalmology |
Exploratory clinical study to examine the efficacy of the simultaneous subthreshold retinal-photocoagulation and the intravitreal injection of VEGF inhibitors for diabetic macular edema |
Link |
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Esophageal-Gastro-Intestinal Surgery |
Examination of the usefulness of the sentinel lymph node navigation for esophageal cancer (SN-EC-Chiba) |
Link |
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Esophageal-Gastro-Intestinal Surgery | Examination of the usefulness of the sentinel lymph node navigation for esoagogastric junctional cancer (SN-JC-Chiba) | Link |
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Hematology | The feasibility study of elotuzumab/lenalidomide maintenance therapy in patients with multiple myeloma after autologous stem cell transplantation: a phase 2 study (EL-M study) | Link |
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Gynecology | Exploratory study on the anti-proliferative effects of metformin on endometrial cancer | Link |
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Neurology | Open-label clinical trial: safety of lacosamide in patients with amyotrophic lateral sclerosis | Link |
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Cardiovascular Medicine | Assessment of Fractional Flow Reserve Using Intraluminal Blood Speckle Observed by Integrated-Backscatter Intravascular Ultrasound | Link |
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Gastroenterology | Safety and efficacy of regorafenib in advanced hepatocellular carcinoma patients who were not included in the RESORCE trial | Link |
Yes |
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Gastroenterology | Safety and efficacy of lenvatinib in Child-Pugh A and B patients with advanced hepatocellular carcinoma including high burden of intrahepatic tumor (LAUNCH) | Link |
Yes |
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Gynecology | Indocyanine green and infrared fluorescence in sentinel lymph node mapping for endometrial cancer and cervical cancer: An exploratory study | Link |
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Esophageal-Gastro-Intestinal Surgery | TAS-102 and Bevacizumab as salvage line chemotherapy for colorectal cancer (SOAC1701) | Link |
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Diabetes, Metabolism and Endocrinology | Effectiveness and safety of Combination therapy of Ranibizumab and LuseOgliflozin in type 2 diabetes with diabetic Macular Edema, a parallel group comparison with the standard Treatment controlled by Glimepiride, multicenter, randomized, open-label trial (COMET Trial) | Link |
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Gastroenterology | A randomized, open, Phase II comparison of the safety and efficacy of a reduced and re-escalated dose of sorafenib versus a reduced and maintained dose of sorafenib in patients with advanced hepatocellular carcinoma | Link |
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Plastic, Reconstructive and Aesthetic Surgery | Comparative test on the effectiveness and safety of B blocker topical treatment with different concentrations of active ingredients against superficial infantile hemangioma | Link |
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Urology | Efficacy and Safety of Ra-223 as 1st line therapy in combination with alternative anti-androgen therapy for bone metastatic CRPC Patients | Link |
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Hematology | Phase II study of efficiency of peripheral blood stem cell harvest using low-dose cyclophosphamide plus G-CSF for multiple myeloma | Link |
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Hematology | Phase II study of efficiency of peripheral blood stem cell harvest using low-dose cyclophosphamide plus G-CSF for POEMS syndrome | Link |
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Japanese-Oriental (Kampo) Medicine | Parallel competitive study in two groups to examine the effects of Kampo Medicines (oren-to) for oral mucositis in patients receiving radiation therapy (Effects of Kampo Medicines (oren-to) for oral mucositis in patients receiving radiation) | Link |
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Hematology | The prospective study to evaluate the efficacy of the combination therapy of inhaled budesonide/formoterol fumarate, clarithromycin, and montelukast in AFO after allogeneic SCT (Chiba AFO-01 study) | Link |
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Esophageal-Gastro-Intestinal Surgery | A randomized phase II study of UFT/LV or TEGAFOX for patient with curatively resected high risk Stage II and Stage III colorectal cancer (SOAC-1101) | Link |
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General Surgery, Hepato-Biliary-Pancreatic Unit | A phase II trial of Down staging Chemotherapy with Nab-paclitaxel plus Gemcitabine in patients with locally advanced pancreatic cancer (CAP-005) | Link |
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Cognitive Behavior Therapy Center | False Safety Behavior Elimination Therapy for Generalized Anxiety Disorder-Randomized Clinical Trial Comparing Cognitive Behavioral Therapy and Pharmacological Treatment. (A pilot study of Cognitive Behavioral Therapy for Generalized Anxiety Disorder.) | Link |
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Clinical Psychiatry | An open-label, randomized controlled study evaluating the effectiveness of Pramipexole extended-release tablets for tardive dystonia patients | Link |
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Cardiovascular Medicine | Performance Evaluation of cardioREPO in stress myocardial perfusion scintigraphy for patients with ischemic heart disease | Link |
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Dermatology | A comparative study of erythema reaction using ultraviolet therapy devices with different irradiance | Link |
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Esophageal-Gastro-Intestinal Surgery | FOLFIRI3 plus panitumumab or FOLFIRI3 plus bevacizumab as consolidation chemotherapy after preoperative chemoradiotherapy in patients with locally advanced rectal cancer; a phase II trial | Link |
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Pediatrics | Ascorbic acid treatment for childhood Charcot-Marie-Tooth disease 1A (Ascorbic acid for CMT1A) | Link |
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Gastroenterology | Usefulness of nasal pressure monitor for sedation in invasive endoscopic procedure:A randomized controlled trial (UNSTOP trial) | Link |
Yes |
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Diabetes, Metabolism and Endocrinology | Prospective, single-center, cross-over trial to verify safety and effectiveness of nicotinamide riboside and pterostilbene for patients with Werner syndrome (EMPOWER) | Link |
Yes |
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Rehabilitation Medicine | Safety and efficacy of Mechanical in-exsufflation for prevention of ventilator-associated pneumonia in an intensive care unit: A single center clinical trial | Link | Yes |
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Gastroenterology | Single arm study to evaluate the safety and efficacy of ramucirumab in patients with advanced hepatocellular carcinoma after failure of lenvatinib treatment | Link | Yes |
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Gynecology | Weekly liposomal doxorubicin and cisplatin chemotherapy for patients with epithelial ovarian cancer, fallopian tube cancer, primary peritoneal cancer, phase I study | Link | |
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Cardiovascular Surgery | The use of wristband type continuous pulse measurement device with artificial intelligence for early detection of paroxysmal atrial fibrillation | Link | Yes |
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Respiratory Medicine | Effect of combination of atomoxetine and oxybutynin for Japanese patients with obstructive sleep apnea syndrome
(Effect of combination treatment of atomoxetine and oxybutynin for Japanese patients with obstructive sleep apnea syndrome) | Link | Yes |
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Cognitive Behavior Therapy Center | Effectiveness of eye-contact training devices for social anxiety disorder: a pilot study | Link | |
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Gastroenterology | Safety and efficacy of glecaprevir and pibrentasvir in patients with hepatitis C virus infection and end-stage renal disease undergoing dialysis; a prostective study | Link | Yes |
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Japanese-Oriental (Kampo) Medicine | Randomized controlled trial of prevention for COVID-19 with Kampo medicines (IMJEDI-P1 Study) | Link | |
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Respiratory Medicine | Examination of the usefulness of pulmonary ventilation and circulatory disorder evaluation technology using a dynamic flat-panel detector system for patients with pulmonary hypertension | Link | |
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Neurological Surgery | Confirmation of safety for patients with traumatic brain injury by transcranial direct current stimulation (TDCSTBI) | Link | Yes |
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Orthopedic Surgery | Clinical effect of NTN tablets on lumbar spinal canal stenosis with low back pain
-Multicenter,Randomized,Active-control open-label trial- | Link | |
| Respiratory Medicine | Effects of olfactory stimulation by L-menthol on dyspnea on exertion in chronic lung disease: A pilot study | Link |
Yes |
| Gastroenterology | Multicenter prospective randomized controlled trial of Vonoprazan and Esomeprazole in initial treatment for reflux esophagitis: Focusing on recurrence during maintenance therapy (VERET study) | Link |
Yes |
| Pediatric Surgery | Prospective study of bezafibrate for post operated bilirary atresia | Link |
Yes |
| Neurology | Multicenter prospective registration and intervention studies for chemotherapy-induced peripheral neuropathy (MiroCIP Study) | Link |
Yes |
| Ophthalmology | Prospective clinical trial on the safety and efficacy of anti-VEGF treatment combined with vitrectomy for diabetic macular edema with insufficient effect of anti-VEGF treatment (Eyl/ Vit trial) | Link |
Yes |
| Allergy and Clinical Immunology | Evaluation for the non-inferiority between bisphosphonate monotherapy and bisphosphonate plus active vitamin D for preventing glucocorticoid induced osteoporosis in Japanese patients with systemic autoimmune diseases; An open-label, multicenter, randomized controlled study | Link |
Yes |
| Respiratory Medicine | Examination of the usefulness of a dynamic flat-panel detector system for patients with chronic pulmonary obstructive disease under the treatment with Tiotropium/Olodaterol | Link |
Yes |
| Allergy and Clinical Immunology | A single-arm, phase II study to evaluate the effect of low-dose atovaquone on the prevention of pneumocystis pneumonia in patients with rheumatic diseases treated with corticosteroids | Link |
Yes |
| Esophageal-Gastro-Intestinal Surgery | A clinical trial to evaluate the usefulness of intraoperative intestinal blood f low assessment using an endoscope for the gastrointestinal tract | Link |
Yes |
| Japanese-Oriental (Kampo) Medicine | Randomized controlled trial of herbal medicine (JPS Gorei Ouge) administration effect related to alcohol metabolism in healthy subjects | Link |
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| Gynecology | Bevacizumab combined chemotherapy with gemcitabine and irinotecan in patients with platinum-refractory/resistant ovarian, fallopian or primary pe ritoneal cancer: a phase II trial | Link |
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| Ophthalmology | A double-blinded, randomised, clinical trial about the effect of rebamipide ophthalmic suspension in dry eye with the Sjogren syndrome patients. (Mucosta trial) | Link |
Yes |
| Respiratory Medicine | Tolerability of oral nutrition supplementation for interstitial lung disease with a tendency toward weight loss | Link |
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| Breast Surgery | Assessment of AI Breast (Anatomical Intelligence for Breast) Accuracy and Reproducibility | Link |
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| Pediatric Surgery | Oral selenium supplementation study for selenium-deficiency patient with intestinal failure | Link |
Yes |
| Neurology | Safety of combination therapy of robot suit HAL and repeptive transcranial magnetic stimulation for freezing gait of Parkinson disease | Link |
Yes |
| Cardiovascular Medicine | Randomized, open-label, controlled study to evaluate the efficacy of angiotensin receptor neprilysin inhibitor in patients with aortic stenosis undergoing transcatheter aortic valve implantation. | Link |
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| Respiratory Medicine | A Randomized phase II trial aimed to assess the usefulness of the francine needle in endobronchial ultrasound-guided transbronchial needle aspiration or biopsy | Link |
Yes |
| Pediatrics | Study of the Effect of Combined Use of Vitamin D in Low-dose-oral immunotherapy for Children with Cow's Milk Allergy Double-Blind, Randomized, Placebo-Controlled Trial | Link |
Yes |
| Gastroenterology | The investigation of prophylactic clip hemorrhage control for colorectal cold snare polypectomy in patients taking anti-thrombotic drugs. (PERCOLD study) | Link |
Yes |
| General Thoracic Surgery | A Single-Center Randomized Controlled Trial Evaluating the Air Leakage of Staple Line Reinforcements in Anatomic Pulmonary Resection (Trial of Evaluating of Air Leakage using Staple Line Reinforcements) | Link |
Yes |
| Pediatrics | An Explorative Study for Finding Optimal Indication Criteria for Immunomodulatory Therapy in Patients with Kawasaki Disease (FORKiDs trial) | Link |
Yes |
| Neurology | Age related cerebral perfusion difference and safty in normal adult study by 123 I-IMP SPECT. | Link |
Yes |
| Ophthalmology | Confirmation of the basic theory of an objective quantitative color lens design system for normal subjects (exploratory study 3) | Link |
Yes |
| Gynecology | A sham-controlled, double-blind and parallel-group study of the efficacy and safety of AT-04 for endometriosis Phase III | Link |
Yes |
| Neurological Surgery | Feasibility Study to confirm the decision to skip post-dilation after Carotid Artery Stenting with the Casper Rx by intravascular ultrasound and angioscopy | Link |
Yes |
| Esophageal-Gastro-Intestinal Surgery | A single-center, single-group exploratory study to investigate whether one-time administration of mixture of RI colloid and dye is as tolerable as standard separate administration of the two drugs for sentinel lymph node navigation in gastric cancer surgery | Link |
Yes |
| Respiratory Medicine | Efficacy of oral nutritional supplementation for interstitial lung disease with a tendency to weight loss | Link |
Yes |
| General Thoracic Surgery | A Single-Center Prospective Randomized Controlled Trial to Evaluate the Prevention of Postoperative Adhesions by Applying Regenerated Oxidized Cellulose Sheets to the Parietal Pleura of Open Chest Wound in Thoracic Surgery | Link |
Yes |
| Diabetes, Metabolism and Endocrinology | Single-center exploratory study: Evaluation of therapeutic impact GLP-1 a gonist on glucose and lipid metabolism and fatty liver disease in obesity u sing genomic information | Link |
Yes |
| Orthopedic Surgery | A Randomized Controlled Trial of Postoperative External Fixation in Posterior Cervical Spine Surgery | Link |
Yes |
| Japanese-Oriental (Kampo) Medicine | An exploratory, single-arm, externally controlled comparative study to evaluate the efficacy and safety of adverse reaction of vaccine prophylaxis for combining maoto and eppikajutsuto in subjects planning to receive the new COVID-19 vaccine | Link |
Yes |
| Esophageal-Gastro-Intestinal Surgery | Evaluation of tolerability and normal baseline data collection for a novel test method for early detection of non-obstructive intestinal membrane ischemia (NOMI) | Link |
Yes |
| Gastroenterology | Study of usability of Gastrointestinal Endoscopy with a Single-Use Endoscope | Link |
Yes |
| Ophthalmology | Exploratory clinical study for early detection of glaucoma using novel evaluation device. | Link |
Yes |
| Respiratory Medicine | Prospective, open-label, interventional study to explore the efficacy of the ghrelin agonist anamorelin in patients with cachexia associated with chronic obstructive pulmonary disease | Link | Yes |
| Cardiovascular Medicine | Effect of acetazolamide and furosemide in combination for acute heart failure with volume overload under sodium glucose co-transportor 2 inhibitor (Combination therapy with acetazolamide and furosemide for acute heart failure) | Link | Yes |
| Allergy and Clinical Immunology | non-randomized, controlled, non-autoimmune disease patient group, open-label study to examine the association between changes in femoral head blood flow and the occurrence of osteonecrosis of femoral head in patients with autoimmune disease treated with corticosteroids. | Link | Yes |
| Cardiovascular Medicine | An Uncontrolled, Open-label, Exploratory Trial Investigating Temporal Changes in Microcirculatory Dysfunction in Patients with Takotsubo Syndrome Using Pressurewire X | Link | Yes |
| Pediatrics | A single-blind, randomized, controlled trial of the effect of kestose intake during pregnancy and lactation women on mother and infant microbiome (Fukushima study 2) | Link | Yes |
| Nephrology | An open-label, single arm, multicenter study to evaluate the safety and efficacy of sacubitril valsartan in patients with chronic heart failure on hemodialysis | Link | Yes |
| Esophageal-Gastro-Intestinal Surgery | An exploratory randomized controlled trial of the clinical efficacy of anamorelin hydrochloride in patients after radical surgery for upper gastric cancer and esophagogastric junction cancer - a phase II trial | Link | Yes |
| Japanese-Oriental (Kampo) Medicine | Exploratory study of Hachimijiogan (pill) for elderly patients with "jinkyo" | Link |
Yes |
| Diabetes, Metabolism and Endocrinology | Randomized multicentered non-blinded study to evaluate benefits of a CGM with abnormal glucose alarm combined with telemedicine compared to SMBG for treating of type 2 diabetes in Japan | Link |
Yes |
| Gastroenterology | A randomized controlled trial of superior understanding of puncture reliability measurement in endoscopic ultrasound-guided tissue acquisition for pancreatic tumors using puncture needles with different tip geometries (SUPREME-TA study) | Link |
Yes |
| Gastroenterology | Clinical Trial on the Usefulness of EOI Forms in Balloom Occluded Retrograde Transvenous Obliteration Phase II | Link |
Yes |
| Cardiovascular Medicine | A non-randomized, multi-center study on the safety and efficacy of single antiplatelet therapy post-left atrial appendage closure using the WATCHMAN FLX Pro device in patients with non-valvular atrial fibrillation(SAPT-LAA) (SAPT-LAA) | Link |
Yes |
| Urology | Clinical research on analysis of pelvic lymph flow in prostate cancer, and establishment of sentinel lymph node search method for pelvic lymph node dissection navigation by ICG fluorescence method using a surgical support robot (Da Vinci Xi): a phase II exploratory clinical study | Link |
Yes |
| Emergency and Critical Care Medicine | The efficacy of peptide-based enteral formula and semi-elemental formula in critically ill patients: a randomized trial | Link |
Yes |
| Esophageal-Gastro-Intestinal Surgery | Exploratory clinical trial on intraoperative intestinal blood flow assessment using ultrasound doppler technique | Link |
Yes |
| Pediatrics | A Multicenter Study to Evaluate the Safety and Efficacy of Intranasal Live Influenza Vaccine in Pediatric Patients with Atopic Dermatitis Treated with Dupilumab | Link |
Yes |
