腫瘍内科では、毎週月曜日に抄読会を行っています。様々な癌腫の最新の臨床試験から薬物動態に関するものまで、幅広い分野の論文を元に討論を行っています。
2014年度抄読会
出席者（敬称略）: 滝口、関根、岩澤、植原、今井、栗本、志村、山本、南、研修医、学部学生
| 月 | 日 | title | |
|---|---|---|---|
| 4 | 21 | N Engl J Med 2013;368:1408-16. | Dose-adjusted EPOCH-rituximab therapy in primary mediastinal B-cell lymphoma. |
| 28 | J Clin Oncol 32:1112-1118. | Role of radiotherapy to bulky disease in elderly patients with aggressive B-cell lymphoma. | |
| 5 | 12 | Lancet Oncol 2014; 15: 106–13 | Etoposide and cisplatin versus irinotecan and cisplatin in patients with limited-stage small-cell lung cancer treated with etoposide and cisplatin plus concurrent accelerated hyperfractionated thoracic radiotherapy (JCOG0202): a randomised phase 3 study. |
| 19 | J Clin Oncol 2008;26:5684-5688. | Randomized comparison of cooked and noncooked diets in patients undergoing remission induction therapy for acute myeloid leukemia. | |
| 26 | J Clin Oncol. 2014;32(18):1902-8. | Randomized Phase III Trial of Erlotinib Versus Docetaxel As Second- or Third-Line Therapy in Patients With Advanced Non–Small-Cell Lung Cancer: Docetaxel and Erlotinib Lung Cancer Trial (DELTA) | |
| 6 | 2 | Lancet Oncol 2014; 15: 164–71 | Single versus multiple fractions of repeat radiation for painful bone metastases: a randomised, controlled, non-inferiority trial. |
| 9 | J Clin Oncol 2014;32:1578-1585 | Provision and discussion of survivorship care plans among cancer survivors: results of a nationally representative survey of oncologists and primary care physicians. | |
| 16 | J Clin Oncol 2014;32:1563-1570. | Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. | |
| 23 | Lancet Oncol 2014; 15: 700–12 | Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. | |
| 30 | J Clin Oncol. 2014;32(22):2328-34. | Dose-Finding and Pharmacokinetic Study to Optimize the Dosing of Irinotecan According to the UGT1A1 Genotype of Patients With Cancer | |
| 7 | 7 | Lancet Oncol. 2014;15(4):396-405 | Carboplatin plus paclitaxel once a week versus every 3 weeks in patients with advanced ovarian cancer (MITO-7): a randomised, multicentre, open-label, phase 3 trial |
| 14 | DMD 39:161–164, 2011 | Delayed elimination of SN-38 in cancer patients with severe renal failure. | |
| 28 | Lancet 2010;376:1147–1154 | Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial | |
| 8 | 4 | N Engl J Med 2014;371:424-433 | Enzaltamide in Metastatic Prostate Cancer before Chemotherapy |
| 11 | J Clin Oncol 2014;32(17):1792-1796 | Pattern of Frequent But Nontargeted Pharmacologic Thromboprophylaxis for Hospitalized Patients With Cancer at Academic Medical Centers: A Prospective, Cross-Sectional, Multicenter Study | |
| 18 | J Clin Oncol 2014;July 28. | Pemetrexed and Cisplatin for the Treatment of Advanced, Persistent, or Recurrent Carcinoma of the Cervix: A Limited Access Phase II Trial of the Gynecologic Oncology Group | |
| 25 | Lancet Oncol 2014;15:143–55 | Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small-cell lung cancer (LUME-Lung 1): a phase 3, double-blind, randomised controlled trial | |
| 9 | 1 | J Clin Oncol 2014;32:1571-1577. | Doxepin Rinse Versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Head and Neck Radiotherapy With or Without Chemotherapy: A Phase III, Randomized, Double-Blind Trial |
| 8 | Lancet 2014; 384: 319–28 | Sorafenib in radioactive iodine-refractory, locally advanced or metastatic diff erentiated thyroid cancer: a randomised, double-blind, phase 3 trial | |
| 22 | Lancet Oncol 2014; 15: 1119–28 | Safety and activity of alectinib against systemic disease and brain metastases in patients with crizotinib-resistant ALK-rearranged non-small-cell lung cancer (AF-002JG): results from the dose-fi nding portion of a phase 1/2 study | |
| 29 | JAMA. 2013;309(13):1359-1367 | Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy. A Randomized Clinical Trial | |
| 10 | 6 | Lancet Oncol 2014;15:1065–1075 | FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer (FIRE-3): a randomised, open-label, phase 3 trial |
| 20 | Clin pharm & Therap 2012;91(1):71-80. | Vandetanib for the Treatment of Thyroid Cancer | |
| 27 | N Engl J Med 2014;371:1609-18. | Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer | |
| 11 | 10 | Lancet Oncol 2014;15:1254–62 | Six versus fewer planned cycles of fi rst-line platinum-based chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual patient data |
| 17 | Intern Med 2013;52: 1173-1176, | Talc Pleurodesis for the Management of Malignant Pleural Effusions in Japan, 肺癌学会報告 | |
| 12 | 1 | Lancet Oncol 2014; 15: 1224–35 | Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial |
| 8 | J Clin Oncol 2014;32:3413-3420. | Aprepitant, Granisetron, and Dexamethasone for Prevention of Chemotherapy-Induced Nausea and Vomiting After High-Dose Melphalan in Autologous Transplantation for Multiple Myeloma: Results of a Transplantation for Multiple Myeloma: Results of a Randomized, Placebo-Controlled Phase III Trial | |
| 15 | Lancet 2014; online | Use of thoracic radiotherapy for extensive stage small-cell lung cancer: a phase 3 randomised controlled trial | |
| 22 | J Clin Oncol 2014; 32:2735-2743 | Phase III Randomized Trial of Induction Chemotherapy in Patients With N2 or N3 Locally Advanced Head and Neck Cancer | |
| 1 | 5 | Cancer 2012;118:3330-6. | Comparison of Doxorubicin and Weekly Paclitaxel Efficacy in Metastatic Angiosarcomas |
| 19 | Lancet Oncol 2015; 16: 36–46 | Global burden of cancer attributable to high body-mass index in 2012: a population-based study | |
| 26 | Lancet Oncol 2014; 15: 1442–50 | Personalised chemotherapy based on tumour marker decline in poor prognosis germ-cell tumours (GETUG 13): a phase 3, multicentre, randomised trial | |
| 2 | 2 | J Clin Oncol 2014;32:3299-3306. | Phase II Study of the Safety and Antitumor Activity of the Hypoxia-Activated Prodrug TH-302 in Combination With Doxorubicin in Patients With Advanced Soft Tissue Sarcoma |
| 9 | J Clin Oncol 2012;30:4148-4154. | Randomized Controlled Trial of Interval-Compressed Chemotherapy for the Treatment of Localized Ewing Sarcoma: A Report From the Children’s Oncology Group | |
| 16 | Radiotherapy and Oncology 113 (2014) 248–253 | Ewing sarcoma in adults treated with modern radiotherapy techniques | |
| 23 | N Engl J Med 2015;372:621-30. | Lenvatinib versus Placebo in Radioiodine Refractory Thyroid Cancer | |
| 3 | 2 | Lancet Oncol 2014; 15: 1215–23 | Cumulative alkylating agent exposure and semen parameters in adult survivors of childhood cancer: a report from the St Jude Lifetime Cohort Study |
| 16 | J Clin Oncol 2015;33. | Paclitaxel Plus Carboplatin Versus Paclitaxel Plus Cisplatin in Metastatic or Recurrent Cervical Cancer: The Open-Label Randomized Phase III Trial JCOG0505 | |
| 23 | J Support Oncol 2011;9:188–195 | Olanzapine Versus Aprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Randomized Phase III Trial | |
| 30 | The Oncologist 2012;17:1439–1449 | The Value of Geriatric Assessments in Predicting Treatment Tolerance and All-Cause Mortality in Older Patients With Cancer |
