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 教室研究業績

　
　

　

　放射線医学教室では画像診断、放射線治療、核医学に関する臨床研究や基礎的研究と、放射線治療の基礎となる放射線生物学に関する研究を行っております。これらの研究成果として過去３年間に公表した内容を以下に記載いたします。これらの研究内容に興味がある方は、是非、ご連絡下さい。

　

 　

　

　

　

２００３年　

  1. Kawata T, Ito H, et al. (2003) Radiation-Induced Chromosome Aberrations in Ataxia Telangiectasia Cell Line: high frequency of deletions and misrejoining detected by fluorescence in situ hybridization. Radiat Res 159:597-603.

  2. Shimada H, Kitabayashi H, et al. (2003) Treatment response and prognosis of patients after recurrence of esophageal cancer. Surgery 133:24-31.

  3. Okada J, Higashitusji Y, et al. (2003) Graphic analysis of 99m-Tc thyroid scintigraphy. Ann Nucl Med 17(3):235-238.

  4. Uno T, Yasuda S, et al. (2003) Preoperative radiation therapy for carcinoma of the oropharynx: Prognostic factors for locoregional control and survival. In vivo 17(2): 239-244.

  5. Uno T, Isobe K, et al. (2003) Radiotherapy for Extranodal, Marginal Zone, B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue Originating in the Ocular Adnexa. A Multiinstitutional, Retrospective Review of 50 Patients. Cancer 98(3):865-71.

  6. Uno T, Aruga T, et al. (2003) Radiation btonchitis in lung cancer patient treated with stereotactic radiation therapy. Radiat Med 21(5)228-231.

  7. Uno T, Sumi M, et al. (2003)

  8. Process of care and preliminary outcome in limited-stage small-cell lung cancer: results of the 1995-1997 patterns of care study in Japan.　Int J Radiat Oncol Biol Phys. 55(3):626-32.

  9. Isobe K, Kawakami H, et al. (2003) Concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma: Is intergroup study 0099 feasuble in Japanese patients? Jpn J Clin Oncol 33(10):497-500.

  10. Isobe K, Kawakami H, et al. (2003) Consolidation radiotherapy following brief chemotherapy for localized diffuse large B-cell lymphom: A prospective study. Leuk Lymph, 44(9):1535-1539.

  11. Saeki N, Uchino Y, et al. (2003) MR imaging study of edema-like change along the optic tract in patients with pituitary region tumors. AJNR. 24(3):336-42.　

  12. Saeki N, Hayasaka M, et al. (2003) Posterior pituitary bright spot in large adenomas: MR assessment of its disappearance or relocation along the stalk.　Radiology 226(2):359-65.

  13. Wu H, Kawata T, et al. (2003) M-Fish analysis of chromosome aberrations in human fibroblasts exposed to energetic iron ions in vitro. Adv Space Res 31:1537-1542.

  14. Wu H, Kawata T, et al. (2003) Truly Incomplete and Complex Exchanges in Prematurely Condensed Chromosomes of Human Fibroblasts Exposed In Vitro to Energetic Heavy Ions. Radiat Res 160:418-424.

  15. Motoori K, Hiruma K, et al. (2003): CT and MR imaging of chondro- blatoma of the temporal bone. Eur J Radiol　Extra49:41-45.

  16. Shingyoji M, Takiguchi Y, et al. (2003) Detection of tumor specific gene expression in bone marrow and peripheral blood from patients with small cell lung carcinoma. Cancer 97(4):1057-62.

  17. Kawai S, Hiroshima K, et al. (2003) Small cell carcinoma of the prostate expressing prostate-specific antidiuretic hormone: An autopsy case report. Path Int 53:892-896.

  18. Hiroshima K, Iyoda A, et al. (2003) Fatal infectious mononucleosis with evidence suggestive of the development of B cell lymphoma. Pathol Int 53:642-648, 2003.

  19. Sugiyama H, Teshima T, et al. (2003) The Patterns of Care Study and Regional Cancer Registry for non-small-cell lung cancer in Japan. Int J Radiat Oncol Biol Phys 56:1005-1012.

  20. 下総良太, 藤本肇, 他 (2003) 生活習慣病の画像診断--腹部実質臓器。臨床画像 19(6): 668-678.

  21. 斎藤正好、金井孝夫、他 (2003) マウス実験腫瘍に対する水溶性プロポリスの抗腫瘍効果について。Biotherapy 17:39-45.  

  22. 伊東久夫 (2003)：放射線は何故癌に効くのかーより効果を上げるためにはー。日本医師会雑誌、130(9):1193-1197.

  23. 磯部公一、宇野　隆、伊東久夫 (2003) 食道癌治療に関する最近の進歩。臨床放射線、48(7):843-850.　

  24. 宇野　隆、磯部公一、伊東久夫 (2003)：子宮頸癌：術後放射線照射のエビデンスは？　臨床婦人科産科　57(2):1494-1497.　

  25. 内田佳孝 (2003)　痴呆の診断：各種痴呆性疾患とアルツハイマー病との鑑別診断を中心に　〜EBMに基づく核医学の選択〜 INNERVISION 18(12):49-54.

  26. 片山　仁、伊東久夫、他 (2003)：放射線治療の新しい流れ。日本医師会雑誌、130(9):1177-1192.　

  27. 伊東久夫、安田茂雄、川田哲也 (2003) 6. 肝細胞癌の治療法と適応 (4) 放射線療法。コンセンサス癌治療、2(3)：158-161.

  28. 伊東久夫 (2003)：放射線は何故癌に効くのかーより効果を上げるためにはー。日本医師会雑誌、130(9):1193-1197.　

  29. 伊東久夫、高野英行 (2003)：4.総論　第4章 主な検査　18.インターベンショナルラジオロジー(血管系治療・非血管系治療)。ダイナミックメディシン２(下条文武、斉藤康編), 西村書店、6:66-69.　

  30. 伊東久夫、北原　宏 (2003)：4.総論　第8章 各科の医師へのアドバイス　12.放射線部から。ダイナミックメディシン２(下条文武、斉藤康編), 西村書店、8:29-30. 

  31. 伊東久夫、宇野　隆 (2003)：食道癌に放射線は効くのか。Knack & pitfalls 食道外科の要点と盲点。文光堂、東京、pp339.        

２００４年　

  1. Kobayashi S, Kazama T, et al. (2004) Hemodynamic and morphologic changes after portal vein embolization: differential effects in central and peripheral zones in the liver on multiphasic computed tomography. J Comput Assist Tomogr. 28(6):804-10.　

  2. Kawata T, Ito H, et al. (2004) G2 chromatid damage and repair kinetics in normal human fibroblast cells exposed to low- or high-LET radiation. Cytogenet Genome Res 104:211-215.

  3. Ogawa K, Shikama N, et al. (2004) Long-term results of radiotherapy for intracranial germinoma: a multi-institutional retrospective review of 126 patients. Int J Radiat Oncol Biol Phys 58(3):705-713, 2004. Takeda A, Shigematsu N, et al. (2004)  Evaluation of novel modified tangential irradiation technique for breast cancer patients using dose–volume histograms. Int J Radiat Oncol Biol Phys 58(4): 1280-1288.

  4. Motoori K, Yamamoto S, et al. (2004) Inter- and intratumoral variability in magnetic resonance imaging of pleomorphic adenoma. An attempt to interpret the variable magnetic resonance findings. J Comput Assist Tomogr 28(2):233-246.

  5. Ueda T, Tobe T, et al. (2004) Selective intra- arterial 3-dimensional computed tomography angiography for preoperative evaluation of nephron-sparing surgery. J Comput Assist Tomogr 28:496-504.

  6. Ikeda M, Motoori K, et al. (2004) Warthin tumor of the parotid gland: Diagnostic value of MR imaging with histopathologic correlation. Am J Neuroradiol 25:1256-1262.

  7. Uno T, Isobe K, et al. (2004) Efficacy and toxicities of concurrent chemoradiation for elderly patients with esophageal cancer. Anticancer Res 24(4):2483-6.　

  8. Isobe K, Uno T, et al. (2004) A case of bronchiolitis obliterans organizing pneumonia syndrome with preceding radiation pneumonitis after breast-conserving therapy. Jpn J Clin Oncol 34(12):755-758 

  9. Isobe K, Uno T, et al. (2004) Radiation therapy for idiopathic orbital myositis: two case reports and literature review. Radiat Med 22(6):429-31.

  10. Sakakibara R, Uchida Y, et al. (2004) Reduced cerebellar vermis activation during urinary storage and micturition in multiple system atrophy: 99mTc-labelled ECD SPECT study.　 Eur J Neurol 11:705-8.　

  11. Kawaguchi O, Kunieda E, et al.　(2004) Adenoid cystic carcinoma with hyperostosis after stereotactic radiosurgery. Radiat Med. 22(3):198-200.

  12. 内田佳孝 (2004) 炎症･サルコイドーシスなど．クリニカルPETの最前線．(伊藤正敏、遠藤啓吾、他編)、先端医療技術研究所、東京、pp142-149.　

  13. 磯部公一、宇野隆、伊東久夫 (2004)胃リンパ腫治療と放射線治療の時期と役割を教えて下さい。放射線治療　専門医に聞く最新の臨床　pp262-264　 ISNB 4-498-06510-7

  14. 磯部公一、宇野隆、伊東久夫 (2004)新WHO分類について教えて下さい。放射線治療　専門医に聞く最新の臨床　pp271-273

  15. 磯部公一、宇野　隆、伊東久夫（2004）：放射線医学と病理学連載９総論、現代の放射線治療。病理と臨床、22(3)309-315.

  16. 宇野　隆、磯部公一、伊東久夫 (2004) 術後照射の適応と方法・治療結果について教えてください。放射線治療　専門医に聞く最新の臨床　pp218-220.  

  17. 宇野　隆、磯部公一、伊東久夫 (2004) 子宮頸部断端癌の治療について教えてください。放射線治療　専門医に聞く最新の臨床　pp221-222.

  18. 宇野　隆，伊東久夫 (2004) 再発子宮頚癌に対する放射線治療の役割．日本婦人科腫瘍学会誌22(4):358-361.　

  19. 伊東久夫、宇野　隆、他　(2004)  子宮頸癌・子宮体癌・卵巣癌の診断と治療　IV 卵巣癌、卵巣癌の治療、放射線療法―概論―。日本臨床増刊号　62(10):560-564.

  20. 伊東久夫、宇野　隆、他 (2004)：子宮体がん治療のCONTROVERSY  6. 放射線療法の適応と限界。産科と婦人科、71(2):183-188.   

  21. 上野直之、磯部公一、他 (2004) リンパ節：悪性リンパ腫の画像による病期診断。臨床画像　20(11):174-185.

 ２００５年

  1.  Oshida K, Nagashima T, et al. (2005) Pharmacokinetic analysis of ductal carcinoma in situ of the breast using dynamic MR mammography. Enr Radiol 15:1353-1360.

  2. Uno T, Ito H, et al. (2005) Postoperative pelvic radiotherapy for cervical cancer patients with positive parametrial invasion. Gynecol Oncol 96:335-340.

  3. Kazama T, Faria SC, et al. (2005) FDG PET in the evaluation of treatment for lymphoma: clinical usefulness and pitfalls. Radiographics 25(1):191-207.

  4. Kazama T, Nakamura S, et al. (2005) Prospective evaluation of pectoralis muscle invasion of breast cancer by MR imaging. Breast ca 12(4): 312-316.

  5. Kazama T, Swanston N, et al. (2005) Effect of colony-stimulating factor and convertional or hogh-dose chemotherapy on FDG uptake in bone marrow. Eur J Nucl Med Mol Imag 32(12):1406-1411.

  6. Mitsuhashi A, Uno T, et al. (2005) Phase 1 study of daily cisplatin and concurrent radiotherapy in patients with cervicla carcinoma. Gynecol Oncol 96:194-197.

  7. Shimofusa R, Fujimoto H, et al. (2005) Diffusion-weighted imaging of prostate ca. J Comput Assist Tomogr 29(2):149-153.

  8. Uchida Y, Minoshima S, et al. (2005) Diagnostic vlaue of FDG PET and salivary gland scintigraphy for parotid tumors. Clin Nucl Med 30(3):170-176.

  9. Motoori K, Iida Y, et al. (2005) MR imaging of salivary duct carcinoma. Am J Neuroradiol 26(5):1201-1206.

  10. Motoori K, Ueda T, et al. (2005) Identification of Warthin tumor – Magnetic resonance imaging versus salivary scintigraphy with technetium-99m pertechnetate. J Comput Assist Tomogr 29(4):206-512.

  11. Kawata T, Ito H, et al. (2005) Caffeie sensitizes nondivising human fibroblasts to X rays by inducing a high frequency of misrepair. Radiat Res 164(4):509-513.

  12. Kawata T, Ito H, et al. (2005) Chromosome aberrration induced by high-LET radiations. Biol Sci Space 18(4):216-223.

  13. Isobe K, Uno T, et al. (2005) Weekly cisplatin administration cocurrent with radiation therapy for locoregionally advanced nasopharyngeal carcinoma. Int J Clin Oncol 10-201-203.

  14. Isobe K, Uno T, et al. (2005) Preoperative chemotherapy and radiation therapy for squamous cell carcinoma of the maxillary sinus. Jpn J Clin Oncol 35(11)633-638. 

  15. Isobe K, Uno T, et al. (2005) Hyperfractionated radiation therapy for locoregionally advanced nasopharyngeal cancer. Jpn J Clin Oncol. 2005 Mar;35(3):116-20.

  16. Ueda T, Ito H, Guermazi A (2005) 23. Preoperative navigation of nephron-sparing surgery. In: Imaging of Kidney Cancer, (ed) Guermazi A, Springer, Berlin, 397-414.

  17. Tomiita M, Ueda T, et al. (2005) Usefulness of magnetic resonance sialography in patients with juvenile Sjogren's syndrome. Clin Exp Rheumatol. 23(4):540-4. 

  18. Kawakami H, Uno T, et al. (2005).　Toxicities and effects of involved-field irradiation with concurrent cisplatin for unresectable carcinoma of the pancreas.　Int J Radiat Oncol Biol Phys. 62(5):1357-62.

  19. Shigematsu N, Shinmoto H, et al. (2005) Successful pregnancy and normal delivery after whole craniospinal irradiation in two patients. Anticancer Res. 25(5):3481-7.

  20. Nabeya Y, Ochiai T, et al. (2005) Neoadjuvant chemoradiotherapy followed by esophagectomy for initially respectable squamous cell carcinoma of  the esophagus with multiple lymph node metastasis. Dis Esophagus 18:388-397. 

  21. Takiguchi Y, Uruma R, et al. (2005) Phase I study of cisplatin and irinotecan combined with concurrent hyperfractionated accelerated thoracic radiotherapy for locally advanced non-small cell lung carcinoma. Int J Clin Oncol 10(4):418-424

  22. Ohashi T, Takeda A, et al. (2005) Differences in pulmonary function before vs. 1 year after hypofractionated stereotactic radiotherapy for small peripheral lung tumors. Int J Radiat Oncol Biol Phys. 62(4):1003-8.

  23. Phongkitkarun S, Kazama T, et al.. (2005) Lymphomatous involvement of gastrointestinal tract:Evaluation by positron emission tomography with 18F-fl uorodeoxyglucose. World J Gastroenterol 11(46):7284- 7289.

  24. 宇野　隆、磯部公一、伊東久夫 (2005)：ハイリスク症例に対する後療法にはadjuvant radio- therapyかadjuvant chemotherapyか。産婦人科の世界、57:427-431.

  25. 金親克彦、本折　健、伊東久夫 (2005)：ワルチン腫瘍のMRI所見。他の腫瘍との比較を含めて。臨床放射線　50(8):969-976.

  26. 上野直之、高野英行 (2005) 専門医試験に役立つ知識：悪性腫瘍が異時性に多発する女性の例。臨床画像　21(7):755-759.

  27. 伊東久夫、宇野　隆、川田哲也 (2005)：J.女性生殖器。放射線治療グリーンマニュアル(久保敦司、土器屋卓志、安藤　裕編)、金原出版、東京、pp238-259